Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8
USERS' SCORE
Good
Based on 34 Reviews
8
Supplement Facts
Serving Size: 3 Vegetarian Capsules
Amount Per Serving
%DV
Magnesium (from 2,000 mg Magtein® magnesium L-threonate)
144 mg
34%
Top Medical Research Studies
9
Magnesium sulfate alleviates postoperative pain
We explored the impact of magnesium sulfate on managing pain following total knee arthroplasty. In a randomized, double-blind trial with 90 patients, half received a blend of analgesics that included magnesium sulfate, while the other half did not.
Following surgery, the results showed that magnesium sulfate helped prolong pain relief and reduced the need for opioids. Patients receiving it experienced less postoperative pain and moved towards recovery more effectively.
Overall, adding magnesium sulfate appears beneficial for postoperative knee pain management.
Following surgery, the results showed that magnesium sulfate helped prolong pain relief and reduced the need for opioids. Patients receiving it experienced less postoperative pain and moved towards recovery more effectively.
Overall, adding magnesium sulfate appears beneficial for postoperative knee pain management.
Read More
9
Magnesium aids postoperative pain relief
We explored the role of magnesium in reducing knee pain following total knee arthroplasty (TKA). In a study involving 119 adults, participants received either an adductor canal block with magnesium and bupivacaine or just bupivacaine.
Those who received magnesium reported significantly lower pain scores and reduced opioid usage in the days after surgery, without experiencing an uptick in nausea or dissatisfaction. This suggests that adding magnesium to local anesthesia could enhance pain management for TKA patients, promoting a smoother recovery.
Those who received magnesium reported significantly lower pain scores and reduced opioid usage in the days after surgery, without experiencing an uptick in nausea or dissatisfaction. This suggests that adding magnesium to local anesthesia could enhance pain management for TKA patients, promoting a smoother recovery.
Read More
9
Magnesium reduces postoperative knee pain
We evaluated the impact of magnesium sulphate on pain levels for 44 patients undergoing staged bilateral total knee arthroplasty.
In this study, the magnesium group received magnesium sulphate while the control group received isotonic saline during their surgeries.
Our findings showed that those who received magnesium experienced significantly lower pain scores compared to the control group, both after their first and second surgeries.
Importantly, magnesium also helped reduce the need for additional pain relief medications in the days following surgery.
In this study, the magnesium group received magnesium sulphate while the control group received isotonic saline during their surgeries.
Our findings showed that those who received magnesium experienced significantly lower pain scores compared to the control group, both after their first and second surgeries.
Importantly, magnesium also helped reduce the need for additional pain relief medications in the days following surgery.
Read More
Most Useful Reviews
7.5
Relieved muscle pain
109 people found this helpful
Best Mg I've ever used! This magnesium is superb! As a naturopath, I’ve tried many kinds of magnesium, but this one truly induces calmness, balance and helps me sleep soundly through the night. It was just a few days before I noticed this change, and now, after about three weeks, my neck and muscle pain has also dissipated. Very pleased with this product. Thank you!
Read More
9
Normalised sleep patterns
11 people found this helpful
High-quality, effective magnesium! I consistently buy magnesium for my family, particularly for my father, who struggles with joint and muscle pain. Initially, the doctor recommended three capsules daily; however, we opted for one prior to bed. Now, my father enjoys undisturbed sleep and does not awaken from pain. The effects were noticeable very quickly, making this form of neuromagnesium a staple in our household.
Read More
9
Life-changing relief
6 people found this helpful
I’m 38 and have suffered from period pain and shoulder pain since 2005. However, since using magnesium L-threonate, my life has transformed! I sleep well and feel more relaxed. I take two tablets morning and night, and I can’t recommend it highly enough—it's a miracle!
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8
- All Researches
9
Magnesium sulfate alleviates postoperative pain
We explored the impact of magnesium sulfate on managing pain following total knee arthroplasty. In a randomized, double-blind trial with 90 patients, half received a blend of analgesics that included magnesium sulfate, while the other half did not.
Following surgery, the results showed that magnesium sulfate helped prolong pain relief and reduced the need for opioids. Patients receiving it experienced less postoperative pain and moved towards recovery more effectively.
Overall, adding magnesium sulfate appears beneficial for postoperative knee pain management.
Following surgery, the results showed that magnesium sulfate helped prolong pain relief and reduced the need for opioids. Patients receiving it experienced less postoperative pain and moved towards recovery more effectively.
Overall, adding magnesium sulfate appears beneficial for postoperative knee pain management.
Read More
9
Magnesium aids postoperative pain relief
We explored the role of magnesium in reducing knee pain following total knee arthroplasty (TKA). In a study involving 119 adults, participants received either an adductor canal block with magnesium and bupivacaine or just bupivacaine.
Those who received magnesium reported significantly lower pain scores and reduced opioid usage in the days after surgery, without experiencing an uptick in nausea or dissatisfaction. This suggests that adding magnesium to local anesthesia could enhance pain management for TKA patients, promoting a smoother recovery.
Those who received magnesium reported significantly lower pain scores and reduced opioid usage in the days after surgery, without experiencing an uptick in nausea or dissatisfaction. This suggests that adding magnesium to local anesthesia could enhance pain management for TKA patients, promoting a smoother recovery.
Read More
9
We evaluated how effective magnesium, especially when combined with bupivacaine, is for managing knee pain after arthroscopy. Our study looked at data from 78 randomized trials involving 4,425 participants.
It turns out that magnesium with bupivacaine is the top performer in easing pain right after surgery and at the 24-hour mark, outperforming other analgesics like morphine.
However, magnesium alone didn’t show significant pain relief. We found that using this combination does not lead to more side effects, making it a safe choice for recovery.
It turns out that magnesium with bupivacaine is the top performer in easing pain right after surgery and at the 24-hour mark, outperforming other analgesics like morphine.
However, magnesium alone didn’t show significant pain relief. We found that using this combination does not lead to more side effects, making it a safe choice for recovery.
Read More
9
Magnesium reduces postoperative knee pain
We evaluated the impact of magnesium sulphate on pain levels for 44 patients undergoing staged bilateral total knee arthroplasty.
In this study, the magnesium group received magnesium sulphate while the control group received isotonic saline during their surgeries.
Our findings showed that those who received magnesium experienced significantly lower pain scores compared to the control group, both after their first and second surgeries.
Importantly, magnesium also helped reduce the need for additional pain relief medications in the days following surgery.
In this study, the magnesium group received magnesium sulphate while the control group received isotonic saline during their surgeries.
Our findings showed that those who received magnesium experienced significantly lower pain scores compared to the control group, both after their first and second surgeries.
Importantly, magnesium also helped reduce the need for additional pain relief medications in the days following surgery.
Read More
9
We looked into how magnesium can help ease knee pain after total knee arthroplasty. In a study of 80 patients, those who received an injection of magnesium sulfate and ropivacaine experienced significantly less pain and needed less morphine compared to those who got a saline injection. This approach not only reduced morphine use in the first 48 hours but also allowed patients to regain movement quicker. Overall, our findings suggest that magnesium may be a beneficial part of pain management in knee surgery.
Read More
User Reviews
USERS' SCORE
Good
Based on 34 Reviews
8
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Relieved muscle pain
109 people found this helpful
Best Mg I've ever used! This magnesium is superb! As a naturopath, I’ve tried many kinds of magnesium, but this one truly induces calmness, balance and helps me sleep soundly through the night. It was just a few days before I noticed this change, and now, after about three weeks, my neck and muscle pain has also dissipated. Very pleased with this product. Thank you!
Read More
9
Normalised sleep patterns
11 people found this helpful
High-quality, effective magnesium! I consistently buy magnesium for my family, particularly for my father, who struggles with joint and muscle pain. Initially, the doctor recommended three capsules daily; however, we opted for one prior to bed. Now, my father enjoys undisturbed sleep and does not awaken from pain. The effects were noticeable very quickly, making this form of neuromagnesium a staple in our household.
Read More
9
Life-changing relief
6 people found this helpful
I’m 38 and have suffered from period pain and shoulder pain since 2005. However, since using magnesium L-threonate, my life has transformed! I sleep well and feel more relaxed. I take two tablets morning and night, and I can’t recommend it highly enough—it's a miracle!
Read More
9
Leg pain relief
5 people found this helpful
My family and I use magnesium together. Although the capsules are large, they are easy to swallow. My daughter had leg muscle pain, but with magnesium, that pain has vanished. I've noticed improvements in her calmness, sleep quality, and academic performance. I appreciate the confidence in the high-quality ingredients.
Read More
10
Bone pain relief
4 people found this helpful
Just awesome! I've felt very comfortable after using it, and my bone pain has disappeared.
Read More
Frequently Asked Questions
9
Near complete recovery
2 people found this helpful
After two weeks of use, I experienced notable relief from TN pain, achieving almost 90% recovery after 8-12 weeks. I recently increased my dosage, nearing 99% recovery. Taking it with food helps mitigate diarrhoea.
9
Knee pain relief
2 people found this helpful
Magnesium is essential and beneficial for muscles, joints, and sleep. After an accident damaged my knee, I could no longer sit on it. However, after a short period of taking magnesium, my knees and overall body improved. I'm thrilled I can now sit on my knees without pain.
9
Fast muscle pain relief
3 people found this helpful
Magnesium Threonate is of very high quality and highly absorbed. It’s a bit pricey but sometimes discounted. Safe for breastfeeding and contains only quality ingredients, no gluten or milk. This magnesium is quickly absorbed, providing relief from muscle pain during pregnancy within 15 minutes of taking it. I strongly recommend this product after trying various types of magnesium. Always consult a doctor beforehand.
7.5
Muscle tension relief
2 people found this helpful
This magnesium has proven to be one of the best types I’ve used over three months. It has alleviated muscle and joint pain, reduced tension, and promoted deep sleep. I take one pill before bed with a large glass of water as it dissolves in water. I’ve also noticed improved concentration since starting. With a package holding 90 tablets, it's sufficient for three months and binds very well.
7.5
Relieved muscle pain
109 people found this helpful
Best Mg I've ever used! This magnesium is superb! As a naturopath, I’ve tried many kinds of magnesium, but this one truly induces calmness, balance and helps me sleep soundly through the night. It was just a few days before I noticed this change, and now, after about three weeks, my neck and muscle pain has also dissipated. Very pleased with this product. Thank you!
9
Normalised sleep patterns
11 people found this helpful
High-quality, effective magnesium! I consistently buy magnesium for my family, particularly for my father, who struggles with joint and muscle pain. Initially, the doctor recommended three capsules daily; however, we opted for one prior to bed. Now, my father enjoys undisturbed sleep and does not awaken from pain. The effects were noticeable very quickly, making this form of neuromagnesium a staple in our household.
9
Life-changing relief
6 people found this helpful
I’m 38 and have suffered from period pain and shoulder pain since 2005. However, since using magnesium L-threonate, my life has transformed! I sleep well and feel more relaxed. I take two tablets morning and night, and I can’t recommend it highly enough—it's a miracle!
9
Leg pain relief
5 people found this helpful
My family and I use magnesium together. Although the capsules are large, they are easy to swallow. My daughter had leg muscle pain, but with magnesium, that pain has vanished. I've noticed improvements in her calmness, sleep quality, and academic performance. I appreciate the confidence in the high-quality ingredients.
0
Increased pain
2 people found this helpful
This product did not assist with my migraine; instead, it heightened the pain. I initially hoped for an improvement, but pain arose at the first trial. I thought it was a coincidence, yet after three attempts, the pain recurred. Unfortunately, this is not the medication for me.
10
Improved condition
3 people found this helpful
This is salvation! I took this magnesium to my mother, who suffers from tonic convulsions, and following her covid recovery, everything worsened, causing terrible convulsive pains. She takes it alongside other medications and a different magnesium form, and I must say, it has significantly improved her condition!
7.5
Improved cognitive ability
13 people found this helpful
Excellent product, top quality! The magnesium is carefully packaged and brewed meticulously. It’s a patented form (Magtein® = Magnesium L-Threonate) that effectively crosses the blood-brain barrier, increasing magnesium levels in the brain. This has enhanced my cognitive ability and reduced migraines as well as lessened muscle pain connected to fibromyalgia. My sleep has improved markedly. I highly recommend it based on my positive experience.
9
Magnesium sulfate alleviates postoperative pain
We explored the impact of magnesium sulfate on managing pain following total knee arthroplasty. In a randomized, double-blind trial with 90 patients, half received a blend of analgesics that included magnesium sulfate, while the other half did not.
Following surgery, the results showed that magnesium sulfate helped prolong pain relief and reduced the need for opioids. Patients receiving it experienced less postoperative pain and moved towards recovery more effectively.
Overall, adding magnesium sulfate appears beneficial for postoperative knee pain management.
Following surgery, the results showed that magnesium sulfate helped prolong pain relief and reduced the need for opioids. Patients receiving it experienced less postoperative pain and moved towards recovery more effectively.
Overall, adding magnesium sulfate appears beneficial for postoperative knee pain management.
8
We examined the impact of magnesium sulfate paired with levobupivacaine on pain relief after total knee arthroplasty (TKA). In our study, 60 patients were divided into two groups: one received the magnesium cocktail, while the other only got levobupivacaine. Our findings revealed that the magnesium group experienced prolonged pain relief, reduced reliance on additional pain medication, and effective management of early postoperative pain. Overall, this suggests that magnesium sulfate could be a valuable addition to pain management protocols following knee surgery.
8
We investigated the effectiveness of an intra-operative injection combining magnesium sulphate and ropivacaine on pain relief after total knee arthroplasty.
Our study involved eighty patients who were divided into two groups. One group received the magnesium and ropivacaine mixture, while the other received a saline control.
The results showed that those receiving the magnesium injection had significantly lower morphine use and better pain scores during the first day after surgery. They also regained mobility quicker than the control group.
Overall, magnesium demonstrated promising benefits for managing post-operative pain.
Our study involved eighty patients who were divided into two groups. One group received the magnesium and ropivacaine mixture, while the other received a saline control.
The results showed that those receiving the magnesium injection had significantly lower morphine use and better pain scores during the first day after surgery. They also regained mobility quicker than the control group.
Overall, magnesium demonstrated promising benefits for managing post-operative pain.
9
We looked into how magnesium can help ease knee pain after total knee arthroplasty. In a study of 80 patients, those who received an injection of magnesium sulfate and ropivacaine experienced significantly less pain and needed less morphine compared to those who got a saline injection. This approach not only reduced morphine use in the first 48 hours but also allowed patients to regain movement quicker. Overall, our findings suggest that magnesium may be a beneficial part of pain management in knee surgery.
References
- Zhu Y, Shen S, Cui L, Wu L, Zhang B. Magnesium sulphate and sodium bicarbonate as additives for periarticular local infiltration analgesia improve pain management after unicompartmental knee arthroplasty: a prospective, double-blind, randomized controlled trial. J Orthop Surg Res. 2024;19:764. doi:10.1186/s13018-024-05233-6
- Xu H, Hao C, Wang X, Du J, Zhang T, et al. Effect of Magnesium Sulfate Infusion on Postoperative Quality of Recovery in Patients Undergoing Total Knee Arthroplasty: A Prospective, Double-Blind, Randomized Controlled Trial. Drug Des Devel Ther. 2024;18:919. doi:10.2147/DDDT.S444896
- Zhao C, Wang L, Chen L, Wang Q, Kang P. Effects of magnesium sulfate on periarticular infiltration analgesia in total knee arthroplasty: a prospective, double-blind, randomized controlled trial. J Orthop Surg Res. 2023;18:301. doi:10.1186/s13018-023-03790-w
- Wang Q, Zhao C, Hu J, Ma T, Yang J, et al. Efficacy of a Modified Cocktail for Periarticular Local Infiltration Analgesia in Total Knee Arthroplasty: A Prospective, Double-Blinded, Randomized Controlled Trial. J Bone Joint Surg Am. 2023;105:354. doi:10.2106/JBJS.22.00614
- Choi JW, Lahori A, Merlo JA, Gill O, Ghoddoussi F, et al. Adductor Canal Blocks With Bupivacaine and Magnesium After Same-day Discharge Total Knee Arthroplasty Improve Postoperative Pain Relief and Decrease Opioid Consumption: A Prospective Randomized Controlled Trial. Clin J Pain. 2022;38:388. doi:10.1097/AJP.0000000000001036
- He Y, He H, Li X, Lei G, Xie D, et al. Intra-Articular Magnesium Plus Bupivacaine Is the Most Effective and Safe Postoperative Analgesic Option Following Knee Arthroscopy: A Network Meta-analysis. Arthroscopy. 2022;38:2897. doi:10.1016/j.arthro.2022.03.013
- Shi L, Zhu H, Ma J, Shi LL, Gao F, et al. Intra-articular magnesium to alleviate postoperative pain after arthroscopic knee surgery: a meta-analysis of randomized controlled trials. J Orthop Surg Res. 2021;16:111. doi:10.1186/s13018-021-02264-1
- Zhao Z, Zhang X, Peng H, Li W, Liu H, et al. Magnesium Sulfate Combined with a Levobupivacaine Periarticular Cocktail for Analgesia in the Early Postoperative Period after Total Knee Arthroplasty. J Knee Surg. 2021;34:1463. doi:10.1055/s-0040-1710364
- Condello V, Filardo G, Madonna V, Andriolo L, Screpis D, et al. Use of a Biomimetic Scaffold for the Treatment of Osteochondral Lesions in Early Osteoarthritis. Biomed Res Int. 2018;2018:7937089. doi:10.1155/2018/7937089
- Shmagel A, Onizuka N, Langsetmo L, Vo T, Foley R, et al. Low magnesium intake is associated with increased knee pain in subjects with radiographic knee osteoarthritis: data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2018;26:651. doi:10.1016/j.joca.2018.02.002
- Shin HJ, Kim EY, Na HS, Kim TK, Kim MH, et al. Magnesium sulphate attenuates acute postoperative pain and increased pain intensity after surgical injury in staged bilateral total knee arthroplasty: a randomized, double-blinded, placebo-controlled trial. Br J Anaesth. 2016;117:497. doi:10.1093/bja/aew227
- Chen Y, Zhang Y, Zhu YL, Fu PL. Efficacy and safety of an intra-operative intra-articular magnesium/ropivacaine injection for pain control following total knee arthroplasty. J Int Med Res. 2012;40:2032.
- Ekmekci P, Bengisun ZK, Akan B, Kazbek BK, Ozkan KS, et al. The effect of magnesium added to levobupivacaine for femoral nerve block on postoperative analgesia in patients undergoing ACL reconstruction. Knee Surg Sports Traumatol Arthrosc. 2013;21:1119. doi:10.1007/s00167-012-2093-4
- Koltka K, Koknel-Talu G, Asik M, Ozyalcin S. Comparison of efficacy of intraarticular application of magnesium, levobupivacaine and lornoxicam with placebo in arthroscopic surgery. Knee Surg Sports Traumatol Arthrosc. 2011;19:1884. doi:10.1007/s00167-011-1497-x
- Chen Y, Zhang Y, Zhu YL, Fu PL. Efficacy and safety of an intra-operative intra-articular magnesium/ropivacaine injection for pain control following total knee arthroplasty. J Int Med Res. 2009;37:1733.
- Farouk S, Aly A. A comparison of intra-articular magnesium and/or morphine with bupivacaine for postoperative analgesia after arthroscopic knee surgery. J Anesth. 2009;23:508. doi:10.1007/s00540-009-0822-8
